Amy Mainzer (born 1974) is an American astronomer, specializing in astrophysical instrumentation and infrared astronomy. She is the Deputy Project Scientist for the Wide-field Infrared Survey Explorer and the Principal Investigator for the NEOWISE project to study minor planets and the proposed Near Earth Object Camera space telescope mission. She has appeared a number of times in the History Channel series The Universe. She also appears in the documentary featurette "Stellar Cartography: On Earth" included on the Star Trek Generations home video release (March 2010). She serves as the science consultant and host for the live-action interstitials on the PBS Kids series Ready Jet Go! debuting Winter 2016.